A. The government approval for the sale of the new drug has not been given.
B. The new drug has not been approved for sale by the government.
C. For the sale of the new drug we have not been given the approval.
D. The new drug was not approved by the government.
Given sentence is a negative sentence of Present Perfect Tense and in active Voice.
Rule :
Subject + (has /have) + not + been + V3 + Other agents.